Thesis: Every comedy movie or skit John C. Reilly is in is funny, because regardless as to what is happening on the screen, you can still laugh at his hilariously constructed face.
Practical Application: Remake all comedy films by digitally placing John C. Reilly's face over every character.
Caveat: Do not make a holocaust movie starring John C. Reilly.
Fun fact: This is nowhere NEAR as creepy as eating at the Black Bear Diner chain, which has proud portraits of it's hairy, fat, bearded founders named "Papa Bear" and "Sugar Bear" hugging each other. The menu then goes on to do describe how much they love to feed everyone they meet.