Child Louie sounds incapable of feeling happiness, while adult Louie sounds like he's happy all the time. Given his looks and talent, well, I mean, one of those two things is way more believable than the other.
I never got the late 80s/early 90s trend of comics getting their own cartoon shows. Rick Moranis was in Ghostbusters and Honey I Shrunk the Kids, and most kids had probably seen an Uncle Buck poster, but what kid had ever heard of Howie Mandel or Louie Anderson?
I think I remember hearing him describe this show as "What my childhood would have been like if my dad wasn't an abusive alcoholic", which made it bad in a entirely different way.